PF-03463275
Chemical Structure Depiction of
PF-03463275
PF-03463275
Compound characteristics
| Compound ID: | CE04-8527 |
| Compound Name: | PF-03463275 |
| Molecular Weight: | 376.86 |
| Molecular Formula: | C19 H22 Cl F N4 O |
| CAS Number: | 1173239-39-8 |
| Smiles: | [H][C@@]12CN(C)C[C@@]2([H])[C@@H]1CN(Cc1ccc(c(c1)[Cl])F)C(c1cn(C)cn1)=O |
| InChI Key: | KYLOBHXXQOZRKK-QDMKHBRRSA-N |
| Short Description: | PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS permeability and may be used to amelior ate cognitive deficits associated with schizophrenia. |
| Pathway: | Neuroscience |
| Target: | GlyT |
| Type of molecule: | Clinical |
| Alias: | PF-3463275 |
| Stock amount: | 159 |