Uprosertib
Chemical Structure Depiction of
Uprosertib
Uprosertib
Compound characteristics
| Compound ID: | CE05-1978 |
| Compound Name: | Uprosertib |
| Molecular Weight: | 429.25 |
| Molecular Formula: | C18 H16 Cl2 F2 N4 O2 |
| CAS Number: | 1047634-65-0 |
| Smiles: | Cn1c(c2cc(C(N[C@@H](Cc3ccc(c(c3)F)F)CN)=O)oc2[Cl])c(cn1)[Cl] |
| InChI Key: | AXTAPYRUEKNRBA-JTQLQIEISA-N |
| Short Description: | Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2. |
| Pathway: | Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling |
| Target: | Akt |
| Type of molecule: | Clinical |
| Alias: | GSK795 , GSK2141795 |
| Stock amount: | 3568 |