Voxtalisib

Chemical Structure Depiction of
Voxtalisib
Pack Size, mg
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Compound characteristics

Compound ID: CE05-3688
Compound Name: Voxtalisib
Molecular Weight: 270.29
Molecular Formula: C13 H14 N6 O
CAS Number: 934493-76-2
Smiles: CCN1C(C(=Cc2c(C)nc(N)nc12)c1cc[nH]n1)=O
InChI Key: RGHYDLZMTYDBDT-UHFFFAOYSA-N
Short Description: Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110gamma with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: mTOR|||PI3K|||DNA-PK
Type of molecule: Clinical
Alias: SAR245409 , XL765
Stock amount: 679
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