Amonafide dihydrochloride

Chemical Structure Depiction of
Amonafide dihydrochloride
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Compound characteristics

Compound ID: CE05-4101
Compound Name: Amonafide dihydrochloride
Molecular Weight: 356.25
Molecular Formula: C16 H17 N3 O2.H Cl.H Cl
CAS Number: 150091-68-2
Smiles: CN(C)CCN1C(c2cccc3cc(cc(C1=O)c23)N)=O.[Cl].[Cl]
InChI Key: AEMLYYQEBPJIEO-UHFFFAOYSA-N
Short Description: Amonafide dihydrochloride is the dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associat ed strand breaks and impaired DNA and RNA synthesis.
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