Larotinib
Chemical Structure Depiction of
Larotinib
Larotinib
Compound characteristics
| Compound ID: | CE05-6507 |
| Compound Name: | Larotinib |
| Molecular Weight: | 488.95 |
| Molecular Formula: | C24 H26 Cl F N4 O4 |
| CAS Number: | 1438072-11-7 |
| Smiles: | [H][C@]12CN(CCCOc3cc4c(Nc5ccc(c(c5)[Cl])F)ncnc4cc3OC)C[C@@]1([H])OCCO2 |
| InChI Key: | UFUKZMIXTOMMLU-ZRZAMGCNSA-N |
| Short Description: | Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR. |
| Pathway: | Tyrosine Kinase/Adaptors|||Angiogenesis|||NF-Kappab|||Immunology/Inflammation|||JAK/STAT signaling |
| Target: | BTK|||EGFR|||Tyrosine Kinases|||IRAK |
| Type of molecule: | Clinical |
| Stock amount: | 988 |