AS1810722
Chemical Structure Depiction of
AS1810722
AS1810722
Compound characteristics
| Compound ID: | CE06-2212 |
| Compound Name: | AS1810722 |
| Molecular Weight: | 477.52 |
| Molecular Formula: | C25 H25 F2 N7 O |
| CAS Number: | 909561-15-5 |
| Smiles: | C1CN(CCN1CC(N)=O)c1ccc(cc1)Nc1ncc2ccn(Cc3cc(cc(c3)F)F)c2n1 |
| InChI Key: | IJFRMEXSGYTWGY-UHFFFAOYSA-N |
| Short Description: | AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a p romising candidate for research into allergic diseases, including asthma and atopic conditions. |
| Pathway: | Metabolism|||JAK/STAT signaling|||Stem Cells |
| Target: | P450|||STAT |
| Stock amount: | 122 |