PPI
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11,568 compounds
Bcl2 PPI Inhibitors Library is small molecules that inhibit regulators of programmed cell death.
8,193 compounds
Shape-Helix Mimetics PPI Library is a set of small-molecule agents. Their design involves the mimicry of side-chain residues on one face of the alpha-helix.
23,943 compounds
Recognition Elements PPI Library includes conformationally constrained analogues of bioactive peptides: gamma-, beta-turns, dipeptide mimetics.
205,497 compounds
PPI Library is a set of small-molecule modulators that have been designed for disrupting PPI and reducing its drawbacks.
23,722 compounds
PPI Tripeptide Mimetics Library is small-molecule PPI inhibitors that mimic significant endogenous tripeptides.
68,388 compounds
PPI Helix Turn 3D Mimetics Library was designed on sp3-enriched scaffolds that mimic key recognition elements of protein secondary structure.
2,679 compounds
Small-molecule compounds that mimic the action of protein and modulates PPI.
36,711 compounds
Small molecules that mimic the action of peptides thus modulating PPI. Protein secondary structures are targets for mimicry.
3,055 compounds
Selective small-molecule PDZ inhibitors. They help to overcome drawbacks of PPI.
19,079 compounds
Library contains nonpeptide small-molecules that inhibit PPI. They are structural mimetics to target proteins.
12,103 compounds
Eccentric PPI Library is a set of unusual ring systems (scaffolds) that lie outside the field of (hetero)aromatic systems.
9,487 compounds
Set of PPI modulators. Cyclic lactam amides result from the Ugi reaction of bifunctional keto carboxylic acids.
24,737 compounds
Alpha-Helix Mimetics Library is a set of peptidomimetics. Alpha-helices are key recognition elements of protein secondary structure.
1,503 compounds
3D Mimetics PPI Library is a set of small-molecule compounds that mimic key recognition elements of protein secondary structure.
Tags
Custom ChemistryNovel Scaffolds and Discovery LibrariesCustom Building Blocks for DNA Encoded LibrariesScale up SynthesisMacrocycle CompoundsIn silico Drug Design (CADD)PROTACADME, DMPKMedicinal ChemistryDNA Encoded Libraries-CDI-CapabilitiesDiscovery BiologyAssay DevelopmentHigh Throughput Screening (HTS)Animal ModelsToxicology and SafetyChemistry, Manufacturing and ControlsPre-Plated SetRepresentative CompoundsNatural-Product3D-PharmacophoreMCE-18RepresentativeSoluble DiversityTargeted DiversitySmartTMAntiviralGPCR3DPhenotypic ScreeningCNS activityTranscription FactorsDrugs LibraryTarget ActivityTherapeutical DiversityCNSIon ChannelsProteases HumanKinases HumanPhosphatases HumanReceptors HumanOpportunistic PathogensCancerCardiovascularMetabolicImmune systemInfectionsMusculoskeletalDigestive systemRespiratory tractOtorhinolaryngologicNervous systemEyeMaleFemaleHemic and lymphaticCongenitalSkinEndocrineAnimalWoundsKinasesProteasesPhosphatasesNuclear receptorsOthersPPI modulatorsReceptor's ligandsEpigeneticMimeticsCyclic compoundsFragmentsPoolChemical classes AgroAllosteric Inhibitors