Protease

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2,886 compounds
Human Proteases Annotated Library is small-molecules that modulate protease activity. Compounds can be either peptidomimetics or chelators of metal ions.
30000 compounds
Proteolytic enzymes are crucial for a variety of biological processes in organisms ranging from lower to higher organisms. Proteases cleave proteins into smaller fragments by catalyzing peptide bonds hydrolysis.
958 compounds
Ubiquitin-specific-processing protease 7 . Based on docking scores and conformation overlays, structures were selected to form the final library
2,751 compounds
USP21 target library
10,000 compounds
Discovery of non-covalent USP30-inhibitors with novel chemotypes.
31,972 compounds
Serine Proteases Inhibitors Library is a set of small-molecule compounds that target serine proteases and can be used in anticancer drug discovery.
7,801 compounds
Set of small-molecule compounds that can target cysteine proteases and be used in drug development for cancer, viral, infections treatment.
6,354 compounds
Papain-like protease Library is a set of drug-like compounds for COVID-19. They inhibit viral replication and the dysregulation of signaling cascades in infected cells.
4,792 compounds
3-chymotrypsin-like protease Library is a set of small-molecule compounds for inhibiting coronavirus replication.
2,016 compounds
Arginase Targeted Library is a set of small-molecule compounds against arginase. This enzyme is implicated in cancer immunosuppression and tumor growth.

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Custom ChemistryNovel Scaffolds and Discovery LibrariesCustom Building Blocks for DNA Encoded LibrariesScale up SynthesisMacrocycle CompoundsIn silico Drug Design (CADD)PROTACADME, DMPKMedicinal ChemistryDNA Encoded Libraries-CDI-CapabilitiesDiscovery BiologyAssay DevelopmentHigh Throughput Screening (HTS)Animal ModelsToxicology and SafetyChemistry, Manufacturing and ControlsPre-Plated SetRepresentative CompoundsNatural-Product3D-PharmacophoreMCE-18RepresentativeSoluble DiversityTargeted DiversitySmartTMAntiviralGPCR3DPhenotypic ScreeningCNS activityTranscription FactorsDrugs LibraryTarget ActivityTherapeutical DiversityCNSIon ChannelsProteases HumanKinases HumanPhosphatases HumanReceptors HumanOpportunistic PathogensCancerCardiovascularMetabolicImmune systemInfectionsMusculoskeletalDigestive systemRespiratory tractOtorhinolaryngologicNervous systemEyeMaleFemaleHemic and lymphaticCongenitalSkinEndocrineAnimalWoundsKinasesProteasesPhosphatasesNuclear receptorsOthersPPI modulatorsReceptor's ligandsEpigeneticMimeticsCyclic compoundsFragmentsPoolChemical classes AgroAllosteric Inhibitors
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