Burger line Burger line Burger line
Logo Logo Logo
Burger line Burger line Burger line
Sign in
Sign in

Swissmedic approves Xadago to treat Parkinson’s Disease


The Swiss Agency for Therapeutic Products (Swissmedic) has approved Xadago (safinamide) for use in Parkinson’s Disease (PD).

Xadago, which is being developed by Zambon and its partner Newron Pharmaceuticals, was approved as add-on therapy to levodopa (L-dopa) alone or in combination with other PD therapies for patients in mid-to late-stage and motor fluctuations.

Xadago features the active substance safinamide, a monoamine oxidase-B (MAO-B) inhibitor.

It blocks the enzyme monoamine oxidase type B which breaks down dopamine, helping to restore dopamine levels in the brain and enhancing the patient's symptoms.

In long-term double-blind controlled studies, Xadago demonstrated significant effects on motor fluctuations without increasing the risk of developing dyskinesia.

Xadago is available as tablets (50 and 100 mg) with treatment starting at a dose of 50 mg a day. The dose may be increased up to 100 mg a day depending on patient's requirement.

Zambon CEO Maurizio Castorina said: "This approval by Swissmedic is a further evidence of the acceptance of the benefits offered by Xadago (safinamide) by another regulatory authority.

"We keep on working to ensure this new chemical entity will be available to all the patients in need of innovative therapies in Parkinson's Disease."

Zambon holds the rights to develop and commercialize safinamide globally, excluding Japan and several other Asian territories.

Parkinson's disease affects around 1% of the population over the age of 55 years, with a male-to-female ratio of 3:2.

Published 16 November 2015

Sjurce: http://processandproduction.pharmaceutical-business-review.com/

0
Cart Subtotal:
Go to cart
You will be able to Pay Online or Request a Quote

We use "cookies*  to ensure the functionality of our website, recognise your browser or device, learn more about your interests, and provide you with essential features and services and for additional purposes, including:

Recognising you when you sign-in to use our services. This allows us to provide you with product recommendations, display personalised content, and provide other customised features and services.
Keeping track of your specified preferences. You may set your preferences through Your Account..
Keeping track of items stored in your shopping basket and personal cabinet.
Conducting research and diagnostics to improve ChemDiv’s content, products, and services.
Delivering content, including ads, relevant to your interests on ChemDiv’s site
Reporting. This allows us to measure and analyse the performance of our services.

By  cookies you give consent to the processing of your personal data, including transfer to third parties. Further information can be found in our privacy policy.

Accept all cookies