An anti-aging medicine that removes senescent cells has been discovered

Japanese scientists have figured out how to stop aging and rejuvenate the body: they have developed a drug that removes old cells from the body

According to Makoto Nakanishi, a professor at the Tokyo University of Medicine Research Institute, 60 years ago, American scientist Leonard Hayflick discovered that cells can divide only a certain number of times, after which this process stops, aging cells begin to accumulate in the body.

Recent studies have shown that the division process can also stop as a result of DNA damage, oxidative stress and other factors. These cells cause inflammation and aging.

In the process, the authors discovered that the GLS1 enzyme is vital for the senescent cell. It is closely related to the process of glutamine metabolism. The enzyme is vital for these cells. Therefore, scientists decided to use its inhibitor (inhibitory substance) to destroy all cells that provoke inflammation, including aging.

The development was tested on mice: as a result, their kidneys began to function better, and serum creatinine and blood urea nitrogen were improved. Changes also occurred in the liver and lungs.

The new drug, according to a professor at the Scientific Research Institute of Medicine at the University of Tokyo Nakanishi, can enter the wide market in 5-10 years.

FEBRUARY 18, 2021

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