WATERTOWN, Mass., April 09, 2026 -- Foghorn® Therapeutics Inc., a clinical-stage biotechnology company pioneering a new class of medicines that treat serious diseases by correcting abnormal gene expression, today announced that it will have multiple oral and poster presentations at the 2026 American Association for Cancer Research (AACR) Annual Meeting being held April 17-22, 2026, in San Diego, California.
FHD-909 Preclinical Data and Oral Presentation
New preclinical data for FHD-909 (LY4050784) reinforcing the potential for expansion opportunities in combination with an anti-PD-1 antibody in SMARCA4 (BRG1)-mutant lung cancer. New preclinical data for Selective SMARCA2 inhibitor FHD-909 will be featured as part of an oral presentation and preclinical data for Selective CBP, Selective EP300, and Selective ARID1B degrader programs will be featured as poster presentations.
"FHD-909 is advancing in the clinic in collaboration with Lilly as the first potential selective SMARCA2 inhibitor for the treatment of SMARCA4-mutant cancers. We are excited to present new, compelling preclinical data further supporting potential expansion opportunities in combination with an anti-PD-1 antibody, as part of Dr. Bellon’s oral presentation at this year’s AACR,” said Adrian Gottschalk, President, and Chief Executive Officer of Foghorn.
Degrader Programs Poster Presentations
The poster presentations at the 2026 AACR Annual Meeting will provide deeper insights into the company's proprietary pipeline beyond their lead programs.
"Poster presentations will also highlight additional preclinical data characterizing our wholly owned Selective CBP, Selective EP300, and Selective ARID1B degrader programs. Collectively, these data underscore the differentiated profiles of our pipeline programs which may translate to improved therapeutic outcomes for difficult to treat cancers with significant unmet need,” added Gottschalk.
