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PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.
Set of RAR receptor antagonists. The retinoic acid receptor is a type of nuclear receptor which can also act as a transcription factor.
Serine Proteases Inhibitors Library is a set of small-molecule compounds that target serine proteases and can be used in anticancer drug discovery.
Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.
Akt Targeted Library is a set of small-molecule inhibitors of the Akt-signaling network. These inhibitors are widely used in cancer treatment.
PRMT Library is set of small-molecule compounds with reported affinity against cancer-assosiated PRMTs.
RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.
PI3K-Targeted Library is a set of small-molecule inhibitors of PI3K signaling pathway. They can be used in effective inhibiting tumor progression.
Set of small-molecule serine/threonine kinases family inhibitors.
Autophagy-Targeted Library is a set of small-molecule modulators for the regulation of autophagy.
PD-1/L1 Library is a set of PD-1 and PD-L1 inhibitors. It is a group of anticancer drugs that block the activity of immune checkpoint proteins.
MEF2-HDAC (class II) Modulators Library is a set of drug-like compounds aimed at modulating PPI of MEF2 with HDAC involved in physiological processes.
Small‐molecule allosteric kinase modulators that target allosteric pockets of kinases outside the conserved ATP‐binding pocket.
TLR-8 Ligands Library is a set of small-molecule TLR-8 agonists. They can be used in adjuvantation research and for the treatment of ovarian cancer.
Developmental Pathway Hh/Wnt Set is inhibitors of the Hedgehog and Wnt-signaling pathways implicated in cancer.
Antimitotic Tubulin Library is a set of small-molecule tubulin binders. These inhibitors are potential antimitotic drugs for anticancer therapy.
Heat shock protein 90 Targeted Library is a set of small-molecule modulators that inhibit the activity of HSP90/70 and can be used as anticancer drugs.
Set of small-molecule compounds that inhibit MCL1 thus restoring the apoptotic pathway in tumor cells.
Indoleamine 2,3-dioxygenase1 Focused Library is a set of small-molecule compounds that can inhibit inappropriate IDO activity in tumours.