Burger line Burger line Burger line
Logo Logo Logo
Burger line Burger line Burger line
Menu
Sign in
Sign in

Nucleoside Mimetics Library

Preferred format:
Desirable size of the custom library selection:
Amount:
Mg
  • Mg
  • uMol
Volume:
ChemDiv’s Nucleoside Mimetics Library contains 2,600 compounds.

Modified nucleosides are useful therapeutic agents being currently used as antitumor, antiviral, and antibiotic agents. A significant variety of modified nucleosides displays potent and selective action against the mentioned diseases. Synthetic acyclic, carbocyclic, C-nucleosides, and modified N-nucleosides have shown remarkable action against AIDS, hepatitis, and Herpes infections.

A significant number of synthetically modified nucleosides were designed as antiretroviral drugs in the therapy of human immunodeficiency virus (HIV) infection. During retroviral infection, the viral RNA is used as a template for proviral DNA synthesis, a process mediated by the viral DNA polymerase better known as reverse transcriptase. The proposed mechanism of action of modified agents such as AZT during viral infection involves the interruption of the viral replication process that occurs between the virus and host, particularly the replication inhibition inside T cells, monocytes, and macrophages. [1]

[1] G. Amaral et al., Synthesis and Characterization of Glycosides. (2007). doi:10.1007/978-0-387-70792-1
0 items in Cart
Cart Subtotal:
Go to cart
You will be able to Pay Online or Request a Quote
Catalog
Services
Company

We use "cookies*  to ensure the functionality of our website, recognise your browser or device, learn more about your interests, and provide you with essential features and services and for additional purposes, including:

Recognising you when you sign-in to use our services. This allows us to provide you with product recommendations, display personalised content, and provide other customised features and services.
Keeping track of your specified preferences. You may set your preferences through Your Account..
Keeping track of items stored in your shopping basket and personal cabinet.
Conducting research and diagnostics to improve ChemDiv’s content, products, and services.
Delivering content, including ads, relevant to your interests on ChemDiv’s site
Reporting. This allows us to measure and analyse the performance of our services.

By  cookies you give consent to the processing of your personal data, including transfer to third parties. Further information can be found in our privacy policy.

Accept all cookies