Madrigal's MGL-3196 shows sustained benefit in mid-stage NASH study; shares up 40% premarket
39% of the responders at week 12 experienced complete resolution of NASH at week 36 compared to 6% for placebo (p=0.001). Fibrosis was resolved in half the patients.
Mean liver fat reduction was 37.0% in the treatment group compared to 8.9% for placebo.
No new safety signals were observed.
A larger Phase 3 with a longer treatment period is next up.
May 31, 2018https://seekingalpha.com/