Sirana Pharma and Pfizer to work on treatment for brittle bone disease
German biotech company Sirana Pharma GmbH has entered into a collaborative research agreement with Pfizer Inc. to investigate the potential identification and validation of a novel treatment concept for a rare bone disease, osteogenesis imperfecta (OI).
Also called brittle bone disease, the condition is currently lacking approved drugs.
Sirana Pharma focuses on the development of treatments for unmet medical needs in muscle and bone diseases. The collaboration will utilize Sirana’s microRNA (miRNA)-targeting approach, which targets substantial regenerative recovery of diseased muscle and bone tissue.
“Combining Sirana’s novel miRNA-targeting approach, and the long-standing experience in musculoskeletal disorders and disease mechanisms of its founders, with the expertise and competencies of Pfizer will allow Sirana to expeditiously evaluate its drug candidates for the treatment of this rare disease and to identify potential candidates for further development,” said Michael Kring, CEO of Sirana Pharma GmbH.
“At Pfizer, we are committed to advancing promising, emerging research – both through our internal capabilities and through collaborations with companies like Sirana – with the goal of bringing potentially life-changing medicines to patients around the world,” said Seng H. Cheng, senior vice president and chief scientific officer, Pfizer Rare Disease.
“We look forward to working together with the Sirana team to further explore this new and innovative investigational approach, utilizing miRNA-targeting for the potential treatment of rare bone diseases.”