Inhibitors for "HOT TARGETS"
The library is intended to represent the "top" molecules while capturing many targets.
We added the "3 stars" chemical probes from chemicalprobes.org We also added the top ranked chemical for targets cf Pharos, with focus on Tchem
We selected 515 molecules on the late stages of preclinical trials. It named “chemical probes” inhibitors as each of them is selective against popular target.
The promise and peril of chemical probes Nature Chemical Biology volume 11, pages 536–541 (2015) Cite this article