of Screening Compounds
Drug Discovery Services
Target libraries of chemical compounds help the scientist to develop new drugs that will act on specific therapeutic targets. Usually the target is a key molecule in pathogenesis, so the screening of ...
ChemDiv offers 4 libraries of compounds acting on G protein-coupled receptors: GPCR Targeted Library (40k compounds), GPCR Annotated Library (5800 compounds, biological data available for ...
Science & Nature Reviews, February 2022. Part II
Neurophysiology Kelava, I., Chiaradia, I., Pellegrini, L. et al. Androgens increase excitatory neurogenic potential in human brain organoids. Nature 602, 112–116 (2022) Sex-based brain dif...
Science & Nature Reviews, February 2022. Part I
Molecular biology Rasmussen, M., Reddy, M., Nolan, R. et al. RNA profiles reveal signatures of future health and disease in pregnancy. Nature 601, 422–427 (2022) Pre-eclampsia is a disorde...
How to save the lives of people with cancer who are not cured
30% of people with cancer die from the exhaustion of the body - cachexia. Cachexia is associated with the inhibition of energy metabolism in adipose and muscle tissues. The tumor rebuilds the func...
The human brain has learned to save energy on signal transmission
Science has long been looking for the very feature that makes the human brain more unique than the brains of other mammals. Previously, this was not lucky: the general plan of the structure and the ce...
Science & Nature Reviews, January 2021. Part II
ChemDiv shares reviews on Nature and Science Journal articles that we found the most exciting this month. Today we observe Molecular biology, COVID-19, Physiology, Genetic Engineering, Proteomics. M...
Microneedle patches: new drug carriers improve cancer treatment
New delivery methods can further improve any drug. In this article, we will talk about patches with microneedles - they simplify any therapy. Inside the microneedles are medicine, but the needles are ...
How to stop cancer: attack on the microtubules
Microtubules are rigid protein filaments that run through the inside of the cell. This is the main element of the cytoskeleton: microtubules separate chromosomes during cell division; coordinate the t...
Central nervous system drugs
Due to the nature of the CNS and the blood-brain barrier (BBB), many properties (both chemical and physical) of compounds aimed at CNS targets differ from those of so-called drug-like ...
Science & Nature Reviews, January 2021. Part I
ChemDiv shares reviews on Nature and Science Journal articles that we found the most exciting this month. Today we observe COVID-19, Molecular biology, Physiology, Neurophysiology, and Embryology. CO...
Scientists have created bacteria that feed cancer-fighting immune cells
The immune system recognizes and destroys all objects that seem foreign, and therefore potentially dangerous. Including immunity fights cancer cells: they mutate and no longer seem familiar to immune ...
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