ACTIVITY DATA AGAINST 5 BACTERIA AND 2 FUNGI IN OUR BRAND NEW LIBRARY

ChemDiv presents a brand new library - Opportunistic Pathogens of Immunocompromised Hosts
Annotated Library (OPICH library), which consists of over 2,500 compounds.

BREAKING WORLD PHARMA NEWS

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ChemDiv presents a brand new library - Opportunistic Pathogens of Immunocompromised Hosts Annotated Library (OPICH library), which consists of over 2,500 compounds.

The library also includes activity data against 5 bacteria and 2 fungi. Each compound is annotated with toxicity data on human embryonic kidney cells as well as human red blood cells.



Opportunistic Infections (OIs) still remain a major cause of morbidity and death with either malignant or non-malignant diseases. Opportunistic Infections (OIs) are defined as infections occurring due to bacteria, fungi, viruses, or parasites that normally do not cause a disease, but become pathogenic when the body’s defense system is impaired. OIs can also be represented by unusually severe infections caused by common pathogens.



The available data package includes:

  • Names of pathogens: Straphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Acinetobacter baumanii, Pseudomonas aeruginosa, Candida albicans, Cryptococcus neoformans var. grubii.

  • Table with Percentile(50%) values of MIC, CC50 (cytotoxicity) and HC10 (haemolytic activity) for each organism.

  • Table with individual MIC, CC50 (cytotoxicity) and HC10 (haemolytic activity) values for each organism, as well as Dmax values.

  • Individual data points for import in in-house databases. Haemolysis also reports the HC50 values, which are used to calculate the HC10 values.

This library is available for immediate shipping and could be conveniently formatted in any type of 96- or 384-well plates.

DOWNLOAD COMPLETE DATABASE


OF 1.6 M STOCK COLLECTION COMPOUNDS
AND 60,000 BUILDING BLOCKS

SEARCH AND ORDER ONLINE:

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FOCUSED, TARGETED, ANNOTATED, DIVERSE LIBRARIES
FROM CHEMDIV

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We will be happy to hear your requests, comments or questions at chemdiv@chemdiv.com

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We will be happy to hear your requests, comments or questions at lt@chemdiv.com or sb@chemdiv.com or chemdiv@chemdiv.com

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