The largest commercially available cardiovascular small molecules library for phenotypic screening.
Challenges in Drug Discovery for Cardiovascular (CV) Diseases.
1) Cardiovascular diseases are the leading cause of death globally.
2) The highest disease economic burden compared to other diseases, and keeps climbing up in all predictive analysis reports.
3) In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD.
4) Together CVD resulted in 17.9 million deaths in 2015, up from 12.3 million in 1990.
5) Recent advances in systems biology have led to multiple new cardiovascular drug targets, that will challenge the unmet needs via new cardiovascular drug development.
Targets space includes:
Adenosine receptors, Adrenergic receptors, Angiotensin-converting enzyme, Cholesteryl ester transfer protein, Dopamine receptor, HMG-CoA reductase, MAP kinase, Vasopressin receptor, Purinergic receptor and others.
Medicinal and Computational Chemistry Dept., ChemDiv, Inc.
12760 High Bluff Dr, San Diego, CA, 92130
Phone: + 1 916 234 0888
Fax: +1 858 794 4931
You can buy this library or customize your own library from our discovery collection of 1 600 000 compounds and 60 000 building blocks.