Burger line Burger line Burger line
Logo Logo Logo
Burger line Burger line Burger line
Sign in
Sign in

Indole Derivatives

Preferred format:
Desirable size of the custom library selection:
  • Mg
  • uMol
ChemDiv's Indole Derivatives Library contains 12,000 compounds.

Heterocyclic compounds play a significant role in various biological processes of human body and many of them are in clinical use because of their diverse, chemical and biological properties. However, indole is one of the most promising pharmacologically active molecules.  Indole is an aromatic heterocyclic organic compound, which has a bicyclic structure - comprising of a benzene ring fused with a pyrrole ring. Due to its chemical reactivity, indole has been willingly modified to obtain a variety of new lead molecules, which has been successfully utilized to obtained novel drug candidates for the treatment of different pharmacological diseases.

Indole-based compounds have medicinal and pharmacological importance in improving human life. These indole derivatives attracted the researcher’s attention because of their diversity. Their biological significance includes anti-inflammatory, antifungal, anti-Alzheimer's, anti-Parkinson's, and anticancer potential. Most of all indole derivatives bind to multiple receptors with high affinity, thus expedite the research on the development of novel biologically active compounds through the various approaches. Indole alkaloids such as tryptamine, alstonine, reserpine, ergotamine, and vincristine are well known for the neurotransmitter, antipsychotic, lowering blood pressure, migraine and cancer chemotherapy, respectively. Some of the important pharmaceutical containing indole moiety are indomethacin, ondansetron, sumatriptan. [1]

[1] P. V. Thanikachalam, R. K. Maurya, V. Garg, and V. Monga, “An insight into the medicinal perspective of synthetic analogs of indole: A review,” Eur. J. Med. Chem., vol. 180, pp. 562–612, 2019, doi: 10.1016/j.ejmech.2019.07.019.
0
Cart Subtotal:
Go to cart
You will be able to Pay Online or Request a Quote

We use "cookies*  to ensure the functionality of our website, recognise your browser or device, learn more about your interests, and provide you with essential features and services and for additional purposes, including:

Recognising you when you sign-in to use our services. This allows us to provide you with product recommendations, display personalised content, and provide other customised features and services.
Keeping track of your specified preferences. You may set your preferences through Your Account..
Keeping track of items stored in your shopping basket and personal cabinet.
Conducting research and diagnostics to improve ChemDiv’s content, products, and services.
Delivering content, including ads, relevant to your interests on ChemDiv’s site
Reporting. This allows us to measure and analyse the performance of our services.

By  cookies you give consent to the processing of your personal data, including transfer to third parties. Further information can be found in our privacy policy.

Accept all cookies