Pop-Science

Target libraries of chemical compounds help the scientist to develop new drugs that will act on specific therapeutic targets. Usually the target is a key molecule in pathogenesis, so the screening of ...

ChemDiv offers 4 libraries of compounds acting on G protein-coupled receptors: GPCR Targeted Library (40k compounds), GPCR Annotated Library (5800 compounds, biological data available for ...

30% of people with cancer die from the exhaustion of the body - cachexia. Cachexia is associated with the inhibition of energy metabolism in adipose and muscle tissues. The tumor rebuilds the func...

Science has long been looking for the very feature that makes the human brain more unique than the brains of other mammals. Previously, this was not lucky: the general plan of the structure and the ce...

New delivery methods can further improve any drug. In this article, we will talk about patches with microneedles - they simplify any therapy. Inside the microneedles are medicine, but the needles are ...

Microtubules are rigid protein filaments that run through the inside of the cell. This is the main element of the cytoskeleton: microtubules separate chromosomes during cell division; coordinate the t...

Due to the nature of the CNS and the blood-brain barrier (BBB), many properties (both chemical and physical) of compounds aimed at CNS targets differ from those of so-called drug-like ...

The immune system recognizes and destroys all objects that seem foreign, and therefore potentially dangerous. Including immunity fights cancer cells: they mutate and no longer seem familiar to immune ...

Epigenetics is a growing and promising area of drug discovery research. To date, efforts in this direction have led to over 100 clinical candidates and seven FDA-approved drugs [1-2]. The main idea be...

Scientists launched regeneration after a heart attack, and healed the heart Almost every tissue in the human body is able to recover from damage, regenerating — growing again. The skin repairs scra...

Gamma-aminobutyric acid (GABA) is familiar to neurophysiologists as an inhibitory neurotransmitter in the central nervous system.

Protein kinase inhibitors are an important class of drugs. The FDA has approved over 70 small molecules with this type of action [1, 2]. Approved kinase inhib...