Chemical Libraries.
Complete List of ChemDiv’s Compound Libraries
New arrivals:
- AI Curated Neurodegenerative Library – 6,156 compounds
- Ferroptosis Library – 9,785 compounds
- SKIN Pathophysiology library – 2,126 compounds
- Library of Hydrophobic Tag-Based Targeted Protein Degraders (HyT-TPDs) – 2,400 compounds
- Transmembrane protein Library – 7,000 compounds
- Immunology Inflammation (I&I) Chemical Library – 12,744 compounds
- Antiobesity library – 11,076 compounds
- Good ADME properties library – 35,019 compounds
- MITOCHONDRIA SPECIFIC LIBRARY – 13,858 compounds
- NOVEL DRUG TARGETS library – 48,530 compounds
- GLP1R library – 13,938 compounds
Annotated libraries:
- Phosphatases – 15354 compounds
- Opportunistic Pathogens of Immunocompromised Hosts Annotated Library – 2,100 compounds
- Validated targets annotated space library – 18025 compounds
- Launched & Clinically Evaluated Drugs Library – 190 compounds
- Target Identification, Phenotypic Screening library (TIPS) – 27,664 compounds
- ChemoGenomic Annotated Library for Phenotypic Screening – 90,959 compounds
- Therapeutical Diversity Annotated Library – 8,500 compounds
- Selective Target Activity Profiling Library – 14,839 compounds
- CNS targets activity set – 7,000 compounds
- Human Ion Channels Annotated Library – 351 compounds
- Human Proteases Annotated Library – 2,886 compounds
- Human Transcription Factors Annotated Library – 5,114 compounds
- Human Receptors Annotated Library – 5,398 compounds
- Human Phosphatases Annotated Library – 209 compounds
- CNS Annotated Library – 704 compounds
Diversity libraries:
- Fast follow-up SAR diverse screening library – 155,000 compounds
- 3D-Pharmacophore Based Diversity Library – 52,000 compounds
- 300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) – 300,000 compounds
- 3D-Diversity Natural-Product-Like Library – 21,000 compounds
- 3D-Biodiversity Library – 34,000 compounds
- MCE-18 Trends in Medicinal Chemistry – 50,820 compounds
- Targeted Diversity Library – 39,646 compounds
- Soluble Diversity Library – 15,500 compounds
- SmartTM Library – 50,213 compounds
- Representative Diversity Libraries – 50,000 / 100,000 / 150,000 compounds
Focused and targeted libraries:
- AI Curated Neurodegenerative Library – 6,156 compounds
- Ferroptosis Library – 9,785 compounds
- GPCR Reference Compounds Library – 8,588 compounds
- Human Kinases Library – 4,245 compounds
- SKIN Pathophysiology library – 15,596 compounds
- Natural inhibitors – 4,947 compounds
- Library of Hydrophobic Tag-Based Targeted Protein Degraders (HyT-TPDs) – 2,400 compounds
- Transmembrane protein Library – 7,000 compounds
- Immunology Inflammation (I&I) Chemical Library – 12,744 compounds
- Antiobesity library – 11,076 compounds
- Good ADME properties library – 35,019 compounds
- MITOCHONDRIA SPECIFIC LIBRARY – 13,858 compounds
- NOVEL DRUG TARGETS library – 48,530 compounds
- DarkKinome – 8,436 compounds
- GLP1R library – 13,938 compounds
- USP21 target library – 2,751 compounds
- RNA-Binding Chemical Space library – 24,000 compounds
- MolGluesLike compounds library – 17,880 compounds
- USP 30 library – 10,000 compounds
- USP7 target library – 958 compounds
- TIM-3 library – 7,000 compounds
- CELMoDs library – 25,000 compounds
- IMiD small molecule library – 2000 compounds
- Aryl hydrocarbon receptor (AHR) modulators library – 16,846 compounds
- tTG2 library – 23,000 compounds
- Kinase Scan Library – 16,913 compounds
- Covalent lysine binder library – 4200 compounds
- Sugar and sugar-like compound library – 356 compounds
- MMP inhibitors – 7415 compounds
- HA2-focused library – 3569 compounds
- G9a TARGETED LIBRARY – 11009 compounds
- CXCR4-Targeted Library – 8899 compounds
- DNMT-targeted library – 33936 compounds
- Stem Cell Modulators library – 16834 compounds
- Lysine-specific histone demethylases (KDM) Library – 3,856 compounds
- Calcium channels focused library – 9298 compounds
- hTERT-Targeted Library – 43379 compounds
- Beta2 adrenoligands – 16630 compounds
- Apoptosis Focused Library – 47,566 compounds
- Antibacterial library – 26,000 compounds
- Covalent serine binders library – 4400 compounds
- miRNA targeted small molecule library – 20,000 compounds
- Protease Library – 30000 compounds
- Transferases – 23001 compounds
- Voltage-gated – 17952 compounds
- Toll-like and Il-1 receptors – 3536 compounds
- Thrombopoietin receptors – 4908 compounds
- Sigma Opioid receptors – 8724 compounds
- Proteases – 22863 compounds
- Phosphodiesterases – 13154 compounds
- Oxidoreductases – 8812 compounds
- Lyases – 19530 compounds
- Ligases – 11828 compounds
- Ligand-gated – 9028 compounds
- Kinases – 18350 compounds
- Isomerases – 1206 compounds
- Epigenetics – 9196 compounds
- GPCR Taste family – 2675 compounds
- GPCR Frizzled family – 3434 compounds
- GPCR Family С – 5071 compounds
- GPCR Family B – 9320 compounds
- GPCR Family A – 24763 compounds
- Analogues of Approved Drugs Library – 1400 compounds
- Privileged Fragments Annotated library – 190,000 compounds
- RORγ Library – 13,000 compounds
- cPLA2 inhibitors – 5000 compounds
- Triazoles – 4000 compounds
- Factor XIa Compounds Library – 6500 compounds
- Ocular Diseases small molecules library – 13,000 compounds
- Covalent Fragments Smart Library – 799 compounds
- Crystallographic and 19F NMR fragment-libraries – 2,109 compounds
- Carbonic Anhydrase II Library – 5,000 compounds
- NOTUM (Wnt signaling) Library – 4,003 compounds
- Inhibitors Library. RNA-Protein Interaction. – 2,111 compounds
- Cysteine Targeted Covalent Library – 39,301 compounds
- Natural Compounds Library – 374 compounds
- 3CLpro Library – 4,792 compounds
- ACE2 Library – 3,051 compounds
- PLpro Library – 6,354 compounds
- Bromodomain Modulators Library – 5,816 compounds
- MCL1 Targeted Library – 12,206 compounds
- Arginase Targeted Library – 2,016 compounds
- Chelators targeting matrix metalloproteinases library – 8,600 compounds
- Autophagy-Targeted Library – 4,550 compounds
- SH2 Library – 12,000 compounds
- CNS Targets – 44,085 compounds
- Eccentric PPI Library – 12,103 compounds
- PPI Inhibitors Tripeptide Mimetics – 23,722 compounds
- Hsp90-Targeted Library – 10,991 compounds
- Epigenetics Focused Set – 25,883 compounds
- DGK Inhibitors Library – 12,000 compounds
- Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library – 32,596 compounds
- Histone Deacetylases (HDAC) Targeted Library – 9,769 compounds
- CNS BBB Library – 23,432 compounds
- Ion Channels Focused Library – 26,421 compounds
- Frequent Hitters Library – 9,000 compounds
- Dark Chemical Matter Library – 25,000 compounds
- Fragments Library – 11,269 compounds
- 3D-Fragment Library – 4,063 compounds
- Natural Product Based Library – 18,500 compounds
- Indoles. Indole Derivatives. Indolic compounds. – 9,753 compounds
- Arginine Library – 2,000 compounds
- Spiro Library – 20,563 compounds
- Beyond the Flatland Library sp3 enriched – 90,769 compounds
- New Agro Library – 46,370 compounds
- Antibacterial Compounds Library – 15,000 compounds
- Anti-infective Library – 19,320 compounds
- Antiparasite Library – 25,376 compounds
- Antifungal Library – 16,824 compounds
- Proprietary Proteome Targeted Libraries – compounds
- STING Agonist Library – 5,939 compounds
- Macl-GPIb alpha Interaction Library – 22,214 compounds
- Glucocorticoid receptors Library – 5,000 compounds
- Adenosine Receptors Targeted Library – 21000 compounds
- Receptor-type Protein Tyrosine Phosphatases Library – 3,900 compounds
- Nucleic Acid Ligands – 9,000 compounds
- Neuropeptide S Library – 3,000 compounds
- Indoleamine 2,3-dioxygenase 1 Focused Library – 6,000 compounds
- Integrin Receptors Targeted library – 1,708 compounds
- BRD4 Targeted Library – 5,000 compounds
- Angiogenesis library – 17,000 compounds
- Chemokine Receptor-Targeted Library – 20,000 compounds
- Covalent Inhibitors Library – 12,563 compounds
- Steroid-like Compounds – 498 compounds
- RNA Isosteric Trinucleotide Mimetics Library – 29,000 compounds
- Epitranscriptome Focused Small Molecule Library – 21,000 compounds
- MCE-18 Trends in Medicinal Chemistry – 50000 compounds
- RAR (Nuclear receptors) Ligands Library – 6,767 compounds
- Regenerative Medicine Focused Library – 23,032 compounds
- Anti-Aging Library – 50,410 compounds
- Lipid Metabolism Library – 9,149 compounds
- Cardiovascular Library – 23,000 compounds
- Anti-Inflammatory Library – 28,000 compounds
- TLR-8 ligands Library – 597 compounds
- PD-1/L1 Library – 491 compounds
- Immunological Library – 7,300 compounds
- Protein Arginine Methyltransferases Library – 31,000 compounds
- Serine Proteases Inhibitors Library – 31,972 compounds
- Cysteine Proteases Inhibitors Library – 7,801 compounds
- MEF2-HDAC (class II) Modulators Library – 4,805 compounds
- Developmental Pathway (Hh/Wnt) Set – 2,230 compounds
- Antimitotic Tubulin Library – 18,000 compounds
- Anticancer Library – 65,000 compounds
- Androgen Receptor Antagonists Library – 4,244 compounds
- CORONAVIRUS Library – 21,145 compounds
- Antiviral HBV Library – 11,000 compounds
- Anti-HIV1 Library – 21,000 compounds
- Antiviral Library – 87,000 compounds
- PI3K-Targeted Library – 19,000 compounds
- C-Met Library – 15,080 compounds
- Type II Kinase Inhibitors Library – 8,000 compounds
- Proline Kinase Library – 2,081 compounds
- KRAS-Targeted Library – 16,000 compounds
- Aurora libraries. Aurora A-B Kinases Targeted Library – 10,000 compounds
- Allosteric Inhibitors – 26,000 compounds
- Akt-Targeted Library – 15,000 compounds
- Protein Kinases Inhibitors Library – 36,324 compounds
- GPCR Targeted Library – 40,000 compounds
- Voltage-Gated Ion Channel-Targeted Library – 4,723 compounds
- Ligand channels. Ligand-Gated Ion Channels Library – 3,743 compounds
- Neurotransmitter Transporter Inhibitors Library – 10,813 compounds
- Purinergic Library – 3,271 compounds
- GABA Library – 7,123 compounds
- CNS Library – 26,000 compounds
- CNS MPO Library – 28,284 compounds
- Purine Based Nucleoside Mimetics Library – 1,156 compounds
- Nucleoside Mimetics Library – 2,292 compounds
- SH2 PTB Focused Library – 5,886 compounds
- MDM2-p53 interaction inhibitors Library – 23,319 compounds
- Inhibitors of beta-Catenin Signaling – 8,000 compounds
- Bcl2-PPI Inhibitors Library – 11,568 compounds
- Recognition Elements PPI Library – 23,943 compounds
- 3D Mimetics PPI Library – 1,503 compounds
- Macrocycles Library – 2,335 compounds
- Peptidomimetics of Beta-Turn Motifs Library – 2,679 compounds
- Alpha-Helix Mimetics Library – 24,737 compounds
- Cyclic Ugi PPI Library – 9,487 compounds
- Nonpeptide Peptidomimetics PPI Library – 19,079 compounds
- PDZ PPI Library – 3,055 compounds
- Peptidomimetic Library – 36,711 compounds
- PPI Helix Turn 3D-Mimetics Library – 68,388 compounds
- Shape Helix Mimetics PPI Library – 8,193 compounds
- Protein-Protein Interaction Library – 205,497 compounds
Preplated libraries:
- Preplated diverse 600K layered set – 600,000 compounds
- 100k Diverse Compounds Pre-Plated Set – 100,000 compounds
Inhibitors and Approved Drugs:
- Inhibitors for "HOT TARGETS" – 515 compounds
- On patent drugs (ONP) – 244 compounds
- Off patent drugs (OFP) – 804 compounds
- Off market drugs (OFM) – 300 compounds
- FDA Approved Drugs – 1891 compounds
- Compounds in Clinical Trials – 1977 compounds
- Approved non FDA Drugs – 1062 compounds
- Complete Stock Database of Drugs and Inhibitors – 41068 compounds
- Repurposing Library – 4541 compounds
- Small Molecule Inhibitors – 52984 compounds
Natural Compounds:
- Natural inhibitors – 4,947 compounds
- Natural Compounds Library – 374 compounds
- Natural Product Based Library – 18,500 compounds
Stock available 1.6M compounds diverse collection:
- Discovery chemistry public available >4Y old (DC) – 1,021,102
- New chemistry public available 3 Y old (NC) – 308,919 compounds
- Innovative chemistry non-exclusive 1Y old (IC ) – 144,047 compounds
Browse and Order Libraries
Complete List of Compound Libraries
Focused and targeted libraries
- 100 predesigned libraries
- 19 therapeutical areas
- Dispatched in any custom format
Active Reference Sets
- 17 annotated libraries
- >180K active compounds
- >25K targets
- >190K activity data
Diversity Libraries
- Perfect diversity scoring by Tanimoto
- Focus on novel chemistry by Markush fragments
- High MCE-18 score
- Available as pre-plated sets and as custom-made selections
Preplated libraries
- Represents 30B virtual space of drug-like and lead-like compounds
- Сompounds passed REOS and PAINS, have optimized solubility and «target diversity» approach
- Compounds from over 70 targeted and focused libraries
- Cherry-pick by plates
- 96 or 384 plates format
Inhibitors and Approved Drugs
- 45K Known inhibitors and drugs
Natural base
- 25 000 Natural-Product-Based compounds and Pure Natural compounds know as inhibitors
Virtual space
- 1B virtual space
See also:
- 1,6M Screening compounds
- 70K Building blocks
- 45k Inhibitors & drugs