Complete List of ChemDiv’s Compound Libraries

New arrivals:

• Crystallographic and 19F NMR fragment-libraries – 2,109 compounds
• Carbonic Anhydrase (CA) II Library – 5,000 compounds
• NOTUM (Wnt Signaling) Library – 4,000 compounds
• 300k Representative Compounds Library (Bemis-Murcko Algorithm) – 300,000 compounds

Annotated libraries:

• Antiviral Annotated Library – 22,775 compounds
• CNS Targets Activity Set – 7,000 compounds
• Therapeutical Diversity Annotated Library   – 2,000 compounds & 6,500
• 3D-Biodiversity Library – 27,659 compounds
• Target Identification, Phenotypic Screening Library (TIPS) – 35,000
• Launched & Clinically Evaluated Drugs Library – 274 compounds
• ChemoGenomic Annotated library for Phenotypic Screening – 99,000
• Selective Target Activity Profiling library – 18,000 compounds
• Human GPCR Annotated Library – 5,800 compounds
• Human Ion Channels Annotated Library – 400 compounds
• Human Kinases Annotated Library – 2,500 compounds
• Human Proteases Annotated Library – 3,000 compounds
• Human Transcription Factors Annotated Library – 5,300 compounds
• Human Receptors Annotated Library – 5,600 compounds
• Human Phosphatases Annotated Library – 225 compounds
• CNS Annotated Library – 773 compounds
• Opportunistic Pathogens of Immunocopromised Hosts Annotated Library – 2,100 compounds

Diversity libraries:

• MCE-18 Trends in Medicinal Chemistry – 50,000 compounds
• 3D-Pharmacophore Based Diversity Library -48,835 compounds
• 3D-Diversity Natural-Product-Like Library -17,656 compounds
• Representative Diversity libraries out of 1,6M stock – 50,000 compounds, 100,000 compounds, 150,000 compounds
• 300k Representative Compounds Library (Bemis-Murcko Algorithm) – 300,000 compounds
• Smart^TM Library – 54,000 compounds
• Soluble Diversity Library – 9,500 compounds
• MEC-18 Trends in Medicinal Chemistry – 50,000 compounds
• Targeted Diversity Library – 45,429 compounds

Focused and targeted libraries:

• PPI CDI Library – 230,000 compounds
• PPI Helix Turn 3D-Mimetics Library – 74,000 compounds
• PPI Tripeptide Mimetics Library – 25,000 compounds
• Peptidomimetic Library – 38,400 compounds
• PDZ PPI Library – 4,000 compounds
• Nonpeptide Peptidomimetics PPI library – 22,000 compounds
• Eccentric PPI Library – 13,000 compounds
• Cyclic Ugi PPI Library – 10,000 compounds
• Alpha-Helix Mimetics Library– 24,737 Compounds
• Peptidomimetics of Beta-Turn Motifs Library – 2,679 compounds
• Macrocycles Library – 3,300 compounds
• 3D Mimetics PPI Library – 1,503 compounds
• Recognition Elements PPI Library – 26,000 compounds
• Bcl2-PPI Inhibitors Library – 11,000 compounds
• Library of Small Molecule Inhibitors of beta-Catenin Signaling – 8,000
• MDM2-p53 interaction inhibitors Library – 23,000 compounds
• SH2 Library – 12,000 compounds
• Library of Small Molecule Modulators & Inhibitors of Bromodomains – 5,816 compounds
• DGK Inhibitors Library – 12,000 compounds
• Focused Epigenetics Set – 30,431 compounds
• Hsp90-Targeted Library – 13,000 compounds
• SH2 PTB Focused Library – 7,000 compounds
• Nucleoside Mimetics Library – 2,600

• Carbonic Anhydrase (CA) II Library – 5,000 compounds
• CNS MPO Library – 30,000 compounds
• CNS Targets Library – 44,000 compounds
• CNS targets activity set – 7,000 compounds
• CNS Library – 26,000 compounds
• CNS BBB Library – 23,000 compounds
• GABA library – 17,915 compounds
• Purinergic Library – 3,500 compounds
• Neurotransmitter Transporter Inhibitors library – 12,000 compounds
• Ion Channels Focused Library – 26,000 compounds
• Ligand-Gated Ion Channels Library – 4,000 compounds
• Voltage-Gated Ion Channel-Targeted Library – 5,000 compounds
• Cardiovascular Library – 23,000 compounds

• GPCR Target Platform Library – 40,000 compounds
• PTPN-targeted-library Library – 33,000 compounds

• Protein Kinases Inhibitors Library – 38,000 compounds
• Akt-Targeted Library – 15,000 compounds
• Allosteric Kinases Inhibitors Library – 22,697 compounds
• Aurora A-B Kinases Library – 10,000 compounds
• KRAS-Targeted Library – 16,000 compounds
• Proline Kinase Library – 2,000 compounds
• Type II Kinase Inhibitors Library – 8,000 compounds
• C-Met Library – 16,000 compounds
• PI3K-Targeted Library – 19,000 compounds

• PLpro Library – 6,442 compounds
• ACE2 Library – 3,051 compound
• 3CLpro Library – 4,792 compounds
• Antiviral Library – 87,043 compounds
• Anti-HIV1 Library – 21,000 compounds
• Antiviral HBV – 11,000 compounds
• CORONAVIRUS Library – 21,145 compounds
• MCL1 Targeted Library Selection – 12,000 compounds

• Androgen Receptor Antagonists Library – 4,244 compounds
• RAR (Nuclear receptors) Ligands Library – 6,000 compounds

• Anticancer Library – 65,000 compounds
• NOTUM (Wnt Signaling) Library – 4,000 compounds
• Antimitotic Tubulin Library – 18,000 compounds
• Developmental Pathway (Hh/Wnt) Set – 2,000 compounds
• MEF2-HDAC (class II) Modulators Library – 6,000 compounds
• Arginase  Targeted Library – 2,000 compounds
• Chelators targeting matrix metalloproteinases library – 9,300 compounds

• Cysteine Targeted Covalent Library – 39,301 compounds
• Cysteine Proteases Inhibitors Library – 8,000 compounds
• Serine Proteases Inhibitors Library – 37,000 compounds
• PRMT Library – 31,000 compounds

• Immunological Library – 7,300 compounds
• PD-1/L1 Library – 500 compounds
• TLR-8 ligands Library – 900 compounds
• Anti-Inflammatory Library – 28,000 compounds
• Regenerative Medicine Focused Library – 23,000 compounds

• Lipid Metabolism Library – 9,000 compounds
• Anti-Aging Library – 50,000 Compounds
• Autophagy-Targeted Library – 17,000 compounds
• RNA Isosteric Trinucleotide Mimetics Library – 29,000 compounds
• Chemokines Library – 20,000 compounds
• Angiogenesis library – 14,449 compounds
• BRD4 targeted library – 5,000 compounds
• Integrin Receptors Targeted library – 2,000 compounds
• Indoleamine 2,3-dioxygenase 1 focused library – 6,000 compounds
• Neuropeptide S Library – 3,000 compounds
• RNA-Protein Interaction Inhibitors Library – 2,111 compounds
• Nucleic acid ligands – 9,000 compounds
• RAR (Nuclear receptors) Ligands Library – 6,000 compounds
• Epitranscriptome Focused Small Molecule Library – 21,000 compounds
• RPTP Targeted Library – 3,900 compounds
• Adenosine Receptors Targeted Library – 19,626 compounds
• Glucocorticoid receptors Library – 5,000 compounds
• Macl-GPIb alpha Interaction Library – 27,000 compounds
• STING Agonist Library – 6,000
• Histone Deacetylases (HDAC) Targeted Library Selection – 9,500

• Antiparasite library – 28,000 compounds
• Anti-infective Library – 20,600 compounds
• New Agro Library – 50,000 compounds
• Antifungal Library – 18,000 compounds
• Antibacterial compounds library – 15,000 compounds

• Covalent inhibitors Library – 12,563 compounds
• Covalent Fragments Smart Library –  799 compounds
• Beyond the Flatland Library sp3 enriched – 100,000 compounds
• Crystallographic and 19F NMR fragment-libraries – 2,109 compounds
• Spiro-library – 19,000 compounds
• Indole Derivatives – 12,000 compounds
• 3D-Diversity Natural-Product-Like Library – 17,656 compounds
• Natural-Product-Based Library – 4,000 compounds
• Natural Compounds Library – 374 compounds
• Steroid-like-compounds – 543 compounds
• 3D-Fragment-Library – 4,063 compounds
• Fragments Library – 11,269 compounds
• Dark Chemical Matter Library – 25,000 Compounds
• Frequent Hitters Library – 9,000 compounds
• Purine Based Nucleoside Library – 1,300 compounds

Stock available 1.6M compounds diverse collection

• Discovery chemistry public available >4Y old (DC)  – 1,021,102
• New chemistry public available 3 Y old (NC) – 308,919 compounds
• Innovative chemistry non-exclusive 1Y old (IC )  – 144,047 compounds